Search on: CASEIN KINASES 
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Descriptor English:   Casein Kinases 
Descriptor Spanish:   Caseína Quinasas 
Descriptor Portuguese:   Caseína Quinases 
Synonyms English:   Casein Kinase  
Tree Number:   D08.811.913.696.620.682.700.140
D12.776.476.150
Definition English:   A group of protein-serine-threonine kinases that was originally identified as being responsible for the PHOSPHORYLATION of CASEINS. They are ubiquitous enzymes that have a preference for acidic proteins. Casein kinases play a role in SIGNAL TRANSDUCTION by phosphorylating a variety of regulatory cytoplasmic and regulatory nuclear proteins. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   2005(1974) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38707 
Unique Identifier:   D047388 

Occurrence in VHL:
 

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